`); let searchUrl = `/search/`; history.forEach((elem) => { prevsearch.find('#prevsearch-options').append(`
${elem} `); }); } $('#search-pretype-options').empty(); $('#search-pretype-options').append(prevsearch); let prevbooks = $(false); [ {title:"Recently Opened Textbooks", books:previous_books}, {title:"Recommended Textbooks", books:recommended_books} ].forEach((book_segment) => { if (Array.isArray(book_segment.books) && book_segment.books.length>0 && nsegments<2) { nsegments+=1; prevbooks = $(`
${book_segment.title} `); let searchUrl = "/books/xxx/"; book_segment.books.forEach((elem) => { prevbooks.find('#prevbooks-options'+nsegments.toString()).append(`
${elem.title} ${ordinal(elem.edition)} ${elem.author} `); }); } $('#search-pretype-options').append(prevbooks); }); } function anon_pretype() { let prebooks = null; try { prebooks = JSON.parse(localStorage.getItem('PRETYPE_BOOKS_ANON')); }catch(e) {} if ('previous_books' in prebooks && 'recommended_books' in prebooks) { previous_books = prebooks.previous_books; recommended_books = prebooks.recommended_books; if (typeof PREVBOOKS !== 'undefined' && Array.isArray(PREVBOOKS)) { new_prevbooks = PREVBOOKS; previous_books.forEach(elem => { for (let i = 0; i < new_prevbooks.length; i++) { if (elem.id == new_prevbooks[i].id) { return; } } new_prevbooks.push(elem); }); new_prevbooks = new_prevbooks.slice(0,3); previous_books = new_prevbooks; } if (typeof RECBOOKS !== 'undefined' && Array.isArray(RECBOOKS)) { new_recbooks = RECBOOKS; for (let j = 0; j < new_recbooks.length; j++) { new_recbooks[j].viewed_at = new Date(); } let insert = true; for (let i=0; i < recommended_books.length; i++){ for (let j = 0; j < new_recbooks.length; j++) { if (recommended_books[i].id == new_recbooks[j].id) { insert = false; } } if (insert){ new_recbooks.push(recommended_books[i]); } } new_recbooks.sort((a,b)=>{ adate = new Date(2000, 0, 1); bdate = new Date(2000, 0, 1); if ('viewed_at' in a) {adate = new Date(a.viewed_at);} if ('viewed_at' in b) {bdate = new Date(b.viewed_at);} // 100000000: instead of just erasing the suggestions from previous week, // we just move them to the back of the queue acurweek = ((new Date()).getDate()-adate.getDate()>7)?0:100000000; bcurweek = ((new Date()).getDate()-bdate.getDate()>7)?0:100000000; aviews = 0; bviews = 0; if ('views' in a) {aviews = acurweek+a.views;} if ('views' in b) {bviews = bcurweek+b.views;} return bviews - aviews; }); new_recbooks = new_recbooks.slice(0,3); recommended_books = new_recbooks; } localStorage.setItem('PRETYPE_BOOKS_ANON', JSON.stringify({ previous_books: previous_books, recommended_books: recommended_books })); build_popup(); } } var whiletyping_search_object = null; var whiletyping_search = { books: [], curriculum: [], topics: [] } var single_whiletyping_ajax_promise = null; var whiletyping_database_initial_burst = 0; //number of consecutive calls, after 3 we start the 1 per 5 min calls function get_whiletyping_database() { //gets the database from the server. // 1. by validating against a local database value we confirm that the framework is working and // reduce the ammount of continuous calls produced by errors to 1 per 5 minutes. return localforage.getItem('whiletyping_last_attempt').then(function(value) { if ( value==null || (new Date()) - (new Date(value)) > 1000*60*5 || (whiletyping_database_initial_burst < 3) ) { localforage.setItem('whiletyping_last_attempt', (new Date()).getTime()); // 2. Make an ajax call to the server and get the search database. let databaseUrl = `/search/whiletype_database/`; let resp = single_whiletyping_ajax_promise; if (resp === null) { whiletyping_database_initial_burst = whiletyping_database_initial_burst + 1; single_whiletyping_ajax_promise = resp = new Promise((resolve, reject) => { $.ajax({ url: databaseUrl, type: 'POST', data:{csrfmiddlewaretoken: "LTuawxZDlX8Hwd6heFd6npxh4SiZJYVBop2xqVBwn0nyoF3XvVQKyDuZIBUyJwuO"}, success: function (data) { // 3. verify that the elements of the database exist and are arrays if ( ('books' in data) && ('curriculum' in data) && ('topics' in data) && Array.isArray(data.books) && Array.isArray(data.curriculum) && Array.isArray(data.topics)) { localforage.setItem('whiletyping_last_success', (new Date()).getTime()); localforage.setItem('whiletyping_database', data); resolve(data); } }, error: function (error) { console.log(error); resolve(null); }, complete: function (data) { single_whiletyping_ajax_promise = null; } }) }); } return resp; } return Promise.resolve(null); }).catch(function(err) { console.log(err); return Promise.resolve(null); }); } function get_whiletyping_search_object() { // gets the fuse objects that will be in charge of the search if (whiletyping_search_object){ return Promise.resolve(whiletyping_search_object); } database_promise = localforage.getItem('whiletyping_database').then(function(database) { return localforage.getItem('whiletyping_last_success').then(function(last_success) { if (database==null || (new Date()) - (new Date(last_success)) > 1000*60*60*24*30 || (new Date('2023-04-25T00:00:00')) - (new Date(last_success)) > 0) { // New database update return get_whiletyping_database().then(function(new_database) { if (new_database) { database = new_database; } return database; }); } else { return Promise.resolve(database); } }); }); return database_promise.then(function(database) { if (database) { const options = { isCaseSensitive: false, includeScore: true, shouldSort: true, // includeMatches: false, // findAllMatches: false, // minMatchCharLength: 1, // location: 0, threshold: 0.2, // distance: 100, // useExtendedSearch: false, ignoreLocation: true, // ignoreFieldNorm: false, // fieldNormWeight: 1, keys: [ "title" ] }; let curriculum_index={}; let topics_index={}; database.curriculum.forEach(c => curriculum_index[c.id]=c); database.topics.forEach(t => topics_index[t.id]=t); for (j=0; j
Solutions
Textbooks
`); } function build_solutions() { if (Array.isArray(solution_search_result)) { const viewAllHTML = userSubscribed ? `View All` : ''; var solutions_section = $(` Solutions ${viewAllHTML} `); let questionUrl = "/questions/xxx/"; let askUrl = "/ask/question/xxx/"; solution_search_result.forEach((elem) => { let url = ('course' in elem)?askUrl:questionUrl; let solution_type = ('course' in elem)?'ask':'question'; let subtitle = ('course' in elem)?(elem.course??""):(elem.book ?? "")+" "+(elem.chapter?"Chapter "+elem.chapter:""); solutions_section.find('#whiletyping-solutions').append(` ${elem.text} ${subtitle} `); }); $('#search-solution-options').empty(); if (Array.isArray(solution_search_result) && solution_search_result.length>0){ $('#search-solution-options').append(solutions_section); } MathJax.typesetPromise([document.getElementById('search-solution-options')]); } } function build_textbooks() { $('#search-pretype-options').empty(); $('#search-pretype-options').append($('#search-solution-options').html()); if (Array.isArray(textbook_search_result)) { var books_section = $(` Textbooks View All `); let searchUrl = "/books/xxx/"; textbook_search_result.forEach((elem) => { books_section.find('#whiletyping-books').append(` ${elem.title} ${ordinal(elem.edition)} ${elem.author} `); }); } if (Array.isArray(textbook_search_result) && textbook_search_result.length>0){ $('#search-pretype-options').append(books_section); } } function build_popup(first_time = false) { if ($('#search-text').val()=='') { build_pretype(); } else { solution_and_textbook_search(); } } var search_text_out = true; var search_popup_out = true; const is_login = false; const user_hash = null; function pretype_setup() { $('#search-text').focusin(function() { $('#search-popup').addClass('show'); resize_popup(); search_text_out = false; }); $( window ).resize(function() { resize_popup(); }); $('#search-text').focusout(() => { search_text_out = true; if (search_text_out && search_popup_out) { $('#search-popup').removeClass('show'); } }); $('#search-popup').mouseenter(() => { search_popup_out = false; }); $('#search-popup').mouseleave(() => { search_popup_out = true; if (search_text_out && search_popup_out) { $('#search-popup').removeClass('show'); } }); $('#search-text').on("keyup", delay(() => { build_popup(); }, 200)); build_popup(true); let prevbookUrl = `/search/pretype_books/`; let prebooks = null; try { prebooks = JSON.parse(localStorage.getItem('PRETYPE_BOOKS_'+(is_login?user_hash:'ANON'))); }catch(e) {} if (prebooks && 'previous_books' in prebooks && 'recommended_books' in prebooks) { if (is_login) { previous_books = prebooks.previous_books; recommended_books = prebooks.recommended_books; if (prebooks.time && new Date().getTime()-prebooks.time<1000*60*60*6) { build_popup(); return; } } else { anon_pretype(); return; } } $.ajax({ url: prevbookUrl, method: 'POST', data:{csrfmiddlewaretoken: "LTuawxZDlX8Hwd6heFd6npxh4SiZJYVBop2xqVBwn0nyoF3XvVQKyDuZIBUyJwuO"}, success: function(response){ previous_books = response.previous_books; recommended_books = response.recommended_books; if (is_login) { localStorage.setItem('PRETYPE_BOOKS_'+user_hash, JSON.stringify({ previous_books: previous_books, recommended_books: recommended_books, time: new Date().getTime() })); } build_popup(); }, error: function(response){ console.log(response); } }); } $( document ).ready(pretype_setup); $( document ).ready(function(){ $('#search-popup').on('click', '.search-view-item', function(e) { e.preventDefault(); let autoCompleteSearchViewUrl = `/search/autocomplete_search_view/`; let objectUrl = $(this).attr('href'); let selectedId = $(this).data('objid'); let searchResults = []; $("#whiletyping-solutions").find("a").each(function() { let is_selected = selectedId === $(this).data('objid'); searchResults.push({ objectId: $(this).data('objid'), contentType: $(this).data('contenttype'), category: $(this).data('category'), selected: is_selected }); }); $("#whiletyping-books").find("a").each(function() { let is_selected = selectedId === $(this).data('objid'); searchResults.push({ objectId: $(this).data('objid'), contentType: $(this).data('contenttype'), category: $(this).data('category'), selected: is_selected }); }); $.ajax({ url: autoCompleteSearchViewUrl, method: 'POST', data:{ csrfmiddlewaretoken: "LTuawxZDlX8Hwd6heFd6npxh4SiZJYVBop2xqVBwn0nyoF3XvVQKyDuZIBUyJwuO", query: $('#search-text').val(), searchObjects: JSON.stringify(searchResults) }, dataType: 'json', complete: function(data){ window.location.href = objectUrl; } }); }); });
FAQs
Most Gram-positive bacteria have a relatively thick (about 20 to 80 nm), continuous cell wall (often called the sacculus), which is composed largely of peptidoglycan (also known as mucopeptide or murein).
What is nag and nam? ›
The peptidoglycan layer in the bacterial cell wall is a crystal lattice structure formed from linear chains of two alternating amino sugars, namely N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM).
What contains a Tetrapeptide that extends from N-acetylglucosamine Nag? ›
Peptidoglycan is a polysaccharide made of two glucose derivatives, N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM), alternated in long chains. The chains are cross-linked to one another by a tetrapeptide that extends off the NAM sugar unit, allowing a lattice-like structure to form.
Which of the following components are found in the cell walls of Gram-positive bacteria but not gram-negative bacteria? ›
Gram-negative bacteria are surrounded by a thin peptidoglycan cell wall, which itself is surrounded by an outer membrane containing lipopolysaccharide. Gram-positive bacteria lack an outer membrane but are surrounded by layers of peptidoglycan many times thicker than is found in the Gram-negatives.
What do Gram positive bacteria contain? ›
Gram-positive bacteria (Figs. 5.25 and 5.26) are characterized by their thick walls, which are composed of peptidoglycans and mucocomplexes containing muramic acid and stain prominently with osmium as 20- to 50-nm thick, electron-dense layers surrounding the plasma membrane.
Do gram-positive bacteria have peptidoglycan? ›
Gram positive bacteria have a thick peptidoglycan layer and no outer lipid membrane whilst Gram negative bacteria have a thin peptidoglycan layer and have an outer lipid membrane.
What are the components of the peptidoglycan layer? ›
(right) A peptidoglycan monomer consists of two joined amino sugars, N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM), with a pentapeptide coming off of the NAM. In S. aureus, the pentapeptide consists of the amino acids L-alanine, D-glutamine, L-lysine, and two D-alanines.
Does peptidoglycan have NAG? ›
Peptidoglycan is a linear polymer of alternating units of two sugar derivatives, N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) (Fig. 1). Peptidoglycan also contain several different amino acids, three of which—d-glutamic acid, d-alanine, and meso-diaminopimelic acid—are not found in proteins.
Is the peptidoglycan composed of NAG and NAM only? ›
Peptidoglycan is made of chains of alternating molecules called N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM). When these two molecules are covalently bonded together, it is called a glycan chain. Like the shingles on our roof, there can be many layers of glycan chains in the peptidoglycan layer.
What are the components of N-acetylglucosamine? ›
N-acetylglucosamine (GlcNAc), which is an acetylated derivative of glucosamine (GlcN), is a components of chitin and glycosaminoglycan (e.g., hyaluronic acid (HA) and chondroitin) and has been widely used in dietary supplements for promoting and maintaining the health of cartilage and bone joints [15-18].
The Composition and Structure of Peptidoglycan
The tetrapeptide side chains, alternatively composed of L- and D-amino acids, are attached in sequence. In Gram-positive bacteria, the composition and sequence of amino acids in the tetrapeptide side chains are diverse.
What is a tetrapeptide composed of? ›
A tetrapeptide is a molecule composed of four amino acids linked together, and it is often used as a model to study the self-aggregation of amyloid peptides in Alzheimer's disease.
What are the components of the Gram-positive cell wall? ›
A thick layer of peptidoglycan and the lack of an outer membrane are the main characteristics of Gram-positive cell walls; instead of lipopolysaccharides, Gram-positive bacteria have lipoteichoic acid and teichoic acid localized in the cell wall.
What peptidoglycan contains? ›
Peptidoglycan is the major structural polymer in most bacterial cell walls and consists of glycan chains of repeating N -acetylglucosamine and N -acetylmuramic acid residues cross-linked via peptide side chains.
What does the cell wall of gram-positive bacteria contain quizlet? ›
Gram positive bacteria have a thick peptidoglycan cell wall with a single internal plasma membrane. They do not contain LPS but they do contain teichoic and lipoteichoic acid. Gram negative bacteria have a thinner peptidoglycan cell wall with an outer membrane and an inner plasma membrane (dual membrane).
What does the cell wall of Gram-positive bacteria contain quizlet? ›
Gram positive bacteria have a thick peptidoglycan cell wall with a single internal plasma membrane. They do not contain LPS but they do contain teichoic and lipoteichoic acid. Gram negative bacteria have a thinner peptidoglycan cell wall with an outer membrane and an inner plasma membrane (dual membrane).
What is the main component of the cell wall in bacteria? ›
The primary component of bacterial cell walls is peptidoglycan, also known as murein. Peptidoglycan is a macromolecule composed of sugars and amino acids.
What is the difference between Gram positive and Gram negative bacteria cell wall? ›
The cell wall of gram-positive bacteria is consisting of thick layers of peptidoglycan. Whereas the cell wall of gram-negative bacteria is consisting of thin layers of peptidoglycan. During the gram staining procedure, a gram-positive cell retains the purple-colored stain. But do not retain the purple colored stain.
Do Gram-positive bacteria have LPS? ›
Lipopolysaccharides (LPS) are characteristic components of the cell wall of Gram negative bacteria; they are not found in Gram positive bacteria. They are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface.
